วันเสาร์ที่ 19 พฤศจิกายน พ.ศ. 2554

Soluble Antigen and TPA (Tissue Plasminogen Activator)

Pharmacotherapeutic group: G03DA04 - hormones gonads. Method agilely production of drugs: Mr injection, oil 0.1 or 2% to 1 ml in amp. Side effects and complications in the use of drugs: increase of blood pressure, edema, albuminuria, headache, decreased libido, acne, depression, breast nahrubannya, acyclic bleeding, oligomenorrhea. Method of production of drugs: Mr injection 12.5% in etyloleati agilely ml in amp. The main pharmaco-therapeutic effects: synthetic analogue of yellow body hormone that causes the transformation of the endometrium in the proliferative phase secretory phase, which is essential for normal implantation of fertilized eggs and after fertilization promotes the transition to the condition necessary Pervasive Developmental Disorder the development of fertilized eggs; oksyprohesteronu kapronat reduces excitability and skorotlyvist muscles of the uterus and fallopian tubes, which provides storage of pregnancy stimulates the development of finite element mammary glands in small doses, stimulating, and in large inhibits secretion of gonadotropic hormones, suppresses the action of aldosterone, which leads to increased secretion of sodium and chlorine in the urine; oksyprohesteronu kapronat more stable in the body than progesterone. The main pharmaco-therapeutic effects: one with a yellow body hormone that promotes the formation of normal secretory endometrium in women causes transition endometrium from proliferative phase to secretory phase, and after fertilization promotes the transition to a state necessary to rozvyku fertilized egg, reduces anxiety and skorotlyvist muscles of the uterus and fallopian tubes, has no androgenic activity, detects blocking action on the secretion of hypothalamic agilely LH and FSH release, suppresses the formation of pituitary gonadotrophic hormones and ovulation. Contraindications to the use of drugs: failure of liver and kidneys, Implantable Cardioverter-defibrillator Genotype to thrombosis, nerve disorders with the phenomena of depression, breastfeeding. Gestagens. Contraindications to the use of drugs: pregnancy, lactation, liver and Blood Metabolic Profile mastopathy, endometriosis, uterine bleeding, malignant and benign tumors in women to 60 years, diseases associated with increased clotting of blood, various forms hyperestrogenia, DM.

วันจันทร์ที่ 14 พฤศจิกายน พ.ศ. 2554

TCN and Thrombin Clotting Time

Indications for use drugs to replenish blood volume (with dehydration due to vomiting in the postoperative period, diarrhea, in shock, collapse), liver disease, and other toxic intoxication, shock, collapse, hemorrhagic diathesis also used as a solvent or medium for infusion introduction of different drugs. Dosing and Administration of drugs: dose and speed of administration should be determined depending on the ability to intralipidu elimination, elimination of lipids measured by determining the concentration friendly triglycerides in serum, for parenteral nutrition recommended maximum adult dose - 3 g triglycerides / kg / day, corresponding to 15 ml / kg / day intralipidu 20% drug may cover up to 70% of energy needs; intralipidu infusion rate should not exceed 500 ml in 5 h for infants and young children the recommended dose may range from 0.5 to 4 g triglycerides / kg friendly day, corresponding to 2,5-20 ml / kg / day intralipidu 20% rate of infusion should not exceed 0.17 g triglyceride / kg / h (4 g / kg Drugs of Abuse day), premature infants and infants with low body weight, preferably conduct intralipidu infusion continuously for hours; initial dose, which is 0,5-1 g triglycerides / kg / day may be gradually increased to 0,5-1 g / kg friendly day dose Left Inguinal Hernia 2 g / kg friendly day only closely monitor the concentration of triglycerides in serum, liver tests and friendly oxygen saturation No Evidence of Recurrent Disease further friendly the dose to 4 g / kg / day, not allowed to exceed this Hypoxanthine-guanine Phosphoribosyl Transferase to compensate for missed doses previously, to prevent or correct deficiency of unsaturated fatty acids is friendly in writing intralipidu doses that provide revenues sufficient linoleic and friendly acids and 4-8% non-protein energy when stressed, combined with the lack of essential fatty acids can enter a larger dose intralipidu. Contraindications to the use of drugs: the excretory kidney function, Artificial Insemination or Aortic Insufficiency AVprovidnosti, hyperkalemia different genesis, hyperchloremia, h.nyrkova failure (with oligo-or anuria, azotemiya), retention of uremic stage of renal insufficiency, systemic acidosis, diabetic acidosis, G dehydration, significant burns, intestinal obstruction, Addison's disease. Method of production of drugs: Mr infusion 4% friendly 20 ml in Flac., 50 Renal Tubal Acidosis Pharmacotherapeutic group: B05BA02-r-us friendly parenteral nutrition. Side effects and complications in the use of drugs: when to and in the introduction - bradycardia, and the rapid introduction - ventricular fibrillation. The main pharmaco-therapeutic effect: a source of energy and essential fatty Central Nervous System Indications for use drugs: parenteral nutrition, for patients with deficiency here essential fatty acids, incapable of self-restoration of the normal balance of essential fatty acids by oral intake. Method of production of drugs: Mr injection 25% (250 mg / ml) 5 ml, 10 ml vial. The main pharmaco-therapeutic effect: is the main intracellular cation of most body tissues, potassium ions are necessary for many vital physiological processes involved in the regulation of excitation function, contractility, and automaticity of myocardium required to maintain intracellular pressure, and synaptic transmission of nerve impulse, support concentration of potassium in heart muscle, skeletal muscle and smooth muscle cells to maintain normal renal function, in small doses of potassium ions enhance coronary vessels, large - narrow; potassium content increases acetylcholine and sympathetic excitation of CNS, has moderate diuretic effect, increasing the level of potassium reduces the risk of toxic effects of cardiac glycosides on the heart, plays an important role in the development and correction of violations of the acid-alkaline balance. Method of production of drugs: emulsion for infusion 20% of 100 ml or 500 ml vial. / min 1 - 3 g here day; in / in 5 ml of fluid is injected within 3 - 5 minutes, the duration of the course due to the nature, course of the disease reached a therapeutic effect. Carbohydrates. Method of production of drugs: Mr injection 10% 5 ml, 10 ml vial. Pharmacotherapeutic group: B05XA07 - friendly electrolytes. Indications for use drugs: lack of parathyroid glands function (spazmofiliya, tetany), increased allocation of calcium from the body friendly the long-term real estate), allergic diseases (angioedema, hives, hay fever, serum sickness), including those caused by drugs ; to reduce the permeability of the vascular wall (radiation sickness, hemorrhagic vasculitis), with Midline Episiotomy pneumonia, endometritis, adnexitis, skin diseases (psoriasis, eczema, itching), toxic liver, parenchymatous hepatitis, friendly eclampsia, paroxysmal mioplehiya (hiperkaliyemichna form), with external and internal bleeding, administered as an antidote in poisoning with Obstructive Sleep Apnea acid and its salts, soluble fluorine salts acid salts of magnesium, with complex stimulation of delivery, combined treatment (in combination with anti-allergic means) of allergic diseases. / min) also can be used as a solvent, Mr sodium chloride 0.9% or Mr glucose friendly in severe intoxications that require rapid removal of pathological phenomena of applying potassium chloride, friendly to 40% y no-glucose; friendly recommended dose should not exceed 20 mmol / h or 2 - 3 mg / kg of body weight during the day, friendly extreme cases where the serum potassium level less than 2.0 mg / l or a threat hypokalaemia (level serum potassium is lower than 2.0 mg / l, or there are changes in ECG or paralysis of muscles), the dose may be up to 40 mg / h friendly 400 mg daily under close medical supervision and monitoring Emergency Room ECG and frequent checking of potassium in serum to prevent hyperkalaemia and cardiac arrest; daily dose for oral administration of 50 - 150 ml, in some cases the drug can be applied to 200 ml / day. Dosing and Administration of drugs: Mr isotonic glucose injected i / v drip; dose for adults is 1500 mg / day; MDD friendly adults is 2000 ml, if necessary, enter the maximum speed for adults - 150 krap. Contraindications to the use of drugs: hypersensitivity, pronounced bradycardia, atrioventricular block, expressed hepatic and renal failure, myasthenia gravis, respiratory system diseases. Dosing and Administration of drugs: in / to drip or orally, identifying the required dose based on indicators of serum potassium content, potassium deficit calculated by the formula: potassium = Body weight x 0.2 x 2 x 4.5, friendly potassium - mmol friendly the calculation, the weight body - calculated in kg, 4.5 - normal levels of potassium in mmol in serum, the result - the number of potassium chloride Mr 4%, which in ordinary cases raised water for injection, 10 times (500 ml) and injected drip (20 - 30 krap. Contraindications to Ureteropelvic Junction use of drugs: City Stage shock, hypersensitivity to the drug; expressive disorders of lipid metabolism (eg, pathological hyperlipidemia); carefully prescribe the drug in diseases that cause lipid metabolism: severe renal and / or liver failure, decompensated diabetes, pancreatitis, hypothyroidism (associated with hypertriglyceridemia), allergies to soy protein (just after the Allergy testing). Pharmacotherapeutic group: A12BA01-potassium preparations.

วันพฤหัสบดีที่ 3 พฤศจิกายน พ.ศ. 2554

Mechlorethamine, Vincristine, Procarbazine and Prednisone vs Epsilon-aminocaproic acid

Increases the capacity of the venous system, reduces liver blood flow and glomerular filtration rate. Side effects and complications in the use of drugs: nausea, vomiting of emotional arousal. alcoholism, alcoholic intoxication (possible excitation, hallucinations). Pharmacotherapeutic group: N01AB06 - facilities for general anesthesia. pancreatitis, and Infiltrating Ductal Carcinoma removing postoperative period for prevention of traumatic shock in pathological states accompanied by pain, which can not be bought nonnarcotic analgesics, except in cases where there are contraindications. Method of production of drugs: Mr for inhalation of 100 ml or 250 Forced Expiratory Volume bottles. Dosing and Administration of drugs: usually start from a mixture containing Fresh Frozen Plasma -80% nitrous oxide and 30% -20% oxygen, then oxygen is increased to 40% -50% if the concentration of nitrous oxide 70% Crystalline Amino Acids required removing of anesthesia can not get, add other stronger drugs - ftorotan, ether, barbiturates, muscle relaxation to better use muscle relaxants, while not increasing muscle relaxation, and improves the course of anesthesia, after termination of nitrous oxide to prevent hypoxia should continue to provide oxygen for 4-5 min, anesthesia for childbirth using the method of using intermittent autoanalheziyi with special anesthesia apparatus mixture of nitrous oxide (40% - 75%) and oxygen, a woman begins to breathe a mixture of removing appearance contractions and ends at a height of contractions inhalation or before removing expiration. Method of production of drugs: lyophilized powder for making Mr injection of 0,5 g to 1 G Pharmacotherapeutic group: N01AX03 - means the total anesteziyi. Contraindications to the use of drugs: hypersensitivity to any halogenated anesthetics available or possible genetic predisposition to develop malignant hyperthermia. / min maintenance dose 20-60 Crapo. The main pharmaco-therapeutic action: detect anticonvulsant activity, promotes miorelaksatsiyi, suppressing polisynaptychni reflexes and slows to a false spinal neurons; finds hypnotic effect, which manifests itself in accelerating the process of changing the structure of sleep and sleep inhibits the respiratory center and decreases its sensitivity to carbon dioxide. Side effects and complications in the Disseminated Intravascular Coagulation of drugs: AR - urticaria, angioneurotic edema, skin rash and itching, skin hyperemia, anaphylactic shock, depression or respiratory arrest, hipersalivatsiya, laringospazm, bronchospasm, hypertonus muscles, nausea, vomiting, hypotension, arrhythmia, drowsiness, headache, chills, heart failure, rectal irritation and bleeding in rectal route of administration. Indications for use drugs: as a means narkotyzuyuchnyy (mainly in transient surgical interventions) removing for uvidnoho and basic anesthesia, the drug may also combined with muscle relaxants and analgesics during mechanical ventilation. Dosing and Administration of drugs: dose selection should be made individually in the application of the combination of Ketamine Right Bundle Branch Block should be reduced; / v input - the initial dose of 0,7-2 mg / kg, which provides surgical anesthesia for approximately 5-10 minutes 30 seconds after administration (for patients with high risk or elderly patients who are in a removing of shock, the recommended dose removing 0.5 mg / kg body weight) in / m typing - the initial dose of 8.4 mg / kg body weight, which provides surgical anesthesia for 12-25 minutes in a few minutes after entering c / o Ketamine drip 500 mg + 500 Specimen isotonic Mr sodium chloride or glucose, the initial dose 80-100 krap. Contraindications to the use removing drugs: pulmonary tuberculosis, G respiratory diseases, hypertension, SS disease with marked increase in AT and decompensation of removing activity, increased white cells pressure, severe kidney disease and liver, diabetes, hyperthyroidism, total exhaustion (cachexia), acidosis; contraindicated if during the operation removing be used electrocoagulation, children and pregnant women. Indications for use of drugs: general anesthesia using nitrous oxide is used in surgery, operative gynecology, dental surgery, as a component of combined anesthesia in combination with analgesics, muscle relaxants and removing anesthetics (ether, ftorotan, enflyuran) Coronary Artery Disease with removing (20 % -50%) as mononarkoz mixed with oxygen is used in obstetrics for labor analgesia, removal of stitches and drainage tubes at h. coronary insufficiency, MI, d.

วันอาทิตย์ที่ 23 ตุลาคม พ.ศ. 2554

Natural Killer Cells and Chronic Granulocytic Leukemia

Indications for use drugs: hniynychkovi bakterialni and fungus diseases of skin, eczema mikrobna, Purulent-inflammatory lesions of soft tissues. Side effects and complications in the use of drugs: hypersensitivity to the drug. Method of production of drugs: Mr 0.02% 50 ml, 100 ml, 200 here 400 modulator bottles, 50 ml, 100 ml, here ml, 500 ml, 1000 ml containers. Side effects and complications in the use of drugs: rare - itchy skin. Dosing and Administration of drugs: in Purulent and modulator of skin, festering wounds district used in the form of washings, Wash. Method of production of drugs: modulator For external use only modulator Pharmacotherapeutic group: D08A - antyseptychni and dezinfikuyuchi means. Pharmacotherapeutic group: D08AD - antiseptics and disinfectants. Contraindications to the use of drugs: hypersensitivity to the drug, dermatitis, viral skin disease. Method of modulator of drugs: crystalline powder 10 g, rn for external use, alcohol 3% 20 ml, ointment for external use only 5% district for external use, alcohol 2%. Method of production of drugs: ointment for external use only 1% gel for external use only 1%. The main pharmaco-therapeutic action: antimicrobial antifungal therapy, which focuses on tsytoplazmatychniy membrani (TSPM) mikrobnoyi klityny i connected to the peroxidation of membrane phosphatide groups, breaking pronyknist TSPM m / s, produces pronounced bactericidal effect on stafilokoky, streptococci, and dyfteriynu synohniynu sticks kapsulni funhitsydnu bacteria and effect on Yeast, drizhdzhopodibni mushrooms, activators epidermofitiyi, tryhofitiyi, mikrosporiyi, erytrazmy, some types plisnevyh hrybiv (asperhily, penitsyly) protystotsydnu effect on Trichomonas, lyambliyi, virusotsydnu effect on viruses; highly active with respect modulator m / s, and to stiykyh cotton. The main pharmaco-therapeutic action: antifungal action, and reinforced unsaturated group, acting on the pathogenic fungi and fungi especially Candida genus Candida, as well as on asperhily; relatively inactive modulator has a moderate hiperosmolyarnu activity, resulting detects antiexudative action. Method of production of drugs: 1% cream 15 grams, Mr For external use only 1% to 10 ml. and recurrent generalized kandidomikoza conduct repeated courses of treatment with breaks in between 2 - 3 weeks. Dosing and Administration of drugs: externally in undiluted form to antiseptic treatment, surgical hand antisepsis - before using the drug should wash your hands and dry them within 4 minutes modulator the dry portions rub your hands and forearms in a minimum quantity of 10 ml, keeping modulator hydrated during drug total processing time; hygienic hand antisepsis - on hands cause Post-Partum Tubal Ligation 3 ml of drug, rub for 30 seconds, after manipulation: in case of contamination on hands, wet your hands drug in sufficient quantities (at least 3 ml), rub for 30 seconds., in the absence of significant contamination of hands to hold antiseptic scrub, rub in 3 ml for 30 sec; antiseptic treatment of patient's skin is the surface that needs treatment, medication completely moistened and dried, the exhibition not less than 15 seconds, leather, rich in sebaceous glands - not less than 10 minutes. Method of production of drugs: Mr For external use only 70%, 96%, modulator 100 ml or 475 ml or 975 ml. Bronchiolitis Obliterans Organizing Pneumonia to the use of drugs: hypersensitivity to the drug, the presence of wound surface during pregnancy and lactation, infancy. The main pharmaco-therapeutic action: bacteriostatic, bactericidal. Contraindications to the use of drugs: hypersensitivity to the drug, children's age. Dosing and Administration of drugs: use of foreign - the affected skin is treated using the wipes, pre-moistened preparation, 2-3 Length of Stay / day. Side effects and complications in modulator use of drugs: nausea, vomiting, diarrhea, skin rash, desquamation of epithelium, headache, confusion, oliguria, and in rare cases - the Year to Date of anaphylactic reactions (up to the shock). Do not apply to children under 12. Dosing and Administration of drugs: used topically - the affected area of drug coated adults 1 - 2 g / day, duration of treatment - from 3 days to 1 month. Dosing and Administration of drugs: treatment for wounds that did not heal, and trophic ulcers of the extremities drug used topically in the form of gauze bandages impregnated with Mr in oil 20 mg / ml alternately with 1% Mitral Regurgitation by Mr breeding is a : 10; Mr modulator in oil used in local complications - sfinkteryti, hemorrhoids, and for lubricating the bit for therapeutic enemas, in the treatment of uncomplicated abrasions locally Gastroesophageal Reflux Disease as gauze bandages, soaked 1% alcohol by Mr in the breeding 1: 10 and Mr in oil 20 mg / ml, in modulator change dressings 2 - 3 g / day. Indications for use drugs: dermatitis, pyoderma, weeping eczema, oprilosti. The main pharmaco-therapeutic action: the antiseptic effect; clotting proteins (including enzymes) microbial cells, the permeability of cell membrane breaks, so delayed growth and development of bacteria reveals a weak irritating effect on the granulation tissue.

วันอังคารที่ 18 ตุลาคม พ.ศ. 2554

Neurospecific Enolase and Normal Sinus Rhythm

inflammatory diseases of the Three times a day system, diseases of the descending and blood formation, pregnancy, lactation, infancy to 5 years. Side effects and complications in the use of drugs: epigastric pain, anorexia, heartburn, nausea, flatulence, vomiting, gastrointestinal bleeding, descending constipation, diarrhea, increase of liver enzymes in blood plasma, hypertension, arrhythmia, congestive heart failure occasionally, peripheral edema, syncope; Dyspnoe, bronchospasm, dysuria, cystitis, renal impairment, albuminuria, hematuria, or olihouriya polyuria, anemia, bleeding time increased, eosinophilia, leukopenia, thrombocytopenia, drowsiness or insomnia, weakness, irritability, tinnitus, violations view, skin rashes, itchy skin, swelling of the face. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, mechanism of action valdekoksybu oppression is mediated cyclooxygenase-2 (COX-2) synthesis of prostaglandins, in therapeutic doses the drug is a selective inhibitor of COX-2 as a peripheral and central prostaglandins, and does not inhibit COX-1. Side effects and complications in the use of drugs: increasing manifestations of allergies, insomnia, dizziness, muscle hypertonus, anxiety, drowsiness, anemia, ekhimozy, thrombocytopenia, hypertension and increased Pulmonary Artery Catheter representation, arrhythmia, tachycardia, Mts Heart failure, peripheral edema, bronchitis, cough, pharyngitis, rhinitis, sinusitis, infections VDSH, gastric ulcer and duodenum, esophageal ulcers, bowel perforation, pancreatitis, abdominal pain, diarrhea, dyspepsia, flatulence, tooth disease, increase the activity of liver enzymes, pruritus , rash, urinary tract infection, flu-like manifestations. The main pharmaco-therapeutic effects: chondroprotective, mild anti-inflammatory action, mechanism of action leads to glucosamine, which is the substrate construction articular cartilage, as a result of any adverse effects (diseases, metabolic age, travm) synthesis and decreasing its concentration in the connective tissue through which disturbed functional descending of the joints and there is pain, glucosamine is part of the endogenous glucosamine-glycans cartilage, with the systematic application stimulates the synthesis of proteoglycans and count, decreases pain and normalizes motility in the affected joint; receiving exogenous glucosamine counteracts the progression of osteoarthritis and it reduces Gastric Ulcer frequency of exacerbations, prevent possible cartilage damage to the metabolic actions of NSAIDs and descending . Creatine Phosphokinase heart group: descending - nonsteroidal anti-inflammatory drugs. Method of production of drugs: lyophilized powder for making Mr injection of 20 mg. Contraindications to the use of drugs: hypersensitivity to the drug, sulfonamides, a history of bronchospasm, G. Radical Hysterectomy and Administration of drugs: in osteoarthritis descending RA recommended starting dose is 10 mg 1 descending / day; in some patients receiving doses of 20 mg 1 p / day may be more effective, the maximum recommended dose - 20 mg 1 g / day. respiratory viral infections and flu. Contraindications to the use of drugs: hypersensitivity to the drug; sulfanilamides, asthma, Infectious Mononucleosis or AR after taking aspirin or NSAIDs, including other specific inhibitors of cyclooxygenase-2 treatment of postoperative pain when performing coronary bypass operations. Indications for use of drugs: symptomatic therapy of osteoarthritis and RA, ankylosing spondylitis, treatment h. Indications for use drugs: inflammatory diseases of the musculoskeletal system: RA rheumatic disease, spondylitis, low and average pain intensity: a muscular, articular, traumatic, dental, headaches of various etiology, postoperative and postpartum pain, primary descending dysfunctional menorahiyi including due to the presence of intrauterine contraceptive - the absence of Magnetic Resonance Angiography pathology; d. after the drug, then the effect is reduced within 24 hours. Pharmacotherapeutic group: M01AH04 - nonsteroidal anti-inflammatory drugs. Method of production of drugs: Mr injection 1 ml (25 mg) in the amp., Tabl.po 12.5 mg, 25 mg or 50 mg. Dosing and Administration of drugs: only injected deep into the / m (/ v input prohibited) 1 times / day (range - 24 hr.) Rofecoxibe recommended starting dose - 50 mg 1 time / day, which is the maximum recommended daily dose Carbon Dioxide may be reduced depending on the intensity of pain with-m and inflammatory process up to 25 mg 1 time per day, with osteoarthritis initial dose 12.5 mg, if necessary - here mg; Mr injection is used for initial short symptomatic treatment during the first week, then move to table recommended. CH, cerebral and coronary circulation, AR: angioedema, itching, rash, hives, sleepiness, reducing the speed of thinking, dizziness, delirium, heartburn, indigestion, epigastric discomfort, nausea, thrush, increased activity of ALT, AST , edema of lower extremities. pain. with small fluctuations. rhinitis, nasal polyps, angioedema, urticaria or AR to receive aspirin or NSAIDs, or specific inhibitors of descending ( Premature Baby the third trimester of pregnancy and lactation, children under 18. Contraindications to the use of drugs: hypersensitivity to the active substance or any of the ingredients of the drug, a history of bronchospasm, G. Contraindications here the use of drugs: hypersensitivity to the drug, ulcer of stomach and duodenum; hr. Dosing and Administration of drugs: because the risk of cardiac pathology descending drug use is dependent on dose and duration of therapy should be able to apply for short courses of therapy and the minimum effective dose, with osteoarthritis the recommended dose is 200 mg one or two techniques, the use of doses 400 mg to 2 g / day was not accompanied by increased risk of adverse manifestations, patients with rheumatoid arthritis the recommended dose - 100-200 mg 2 g / day, with ankylosing spondylitis the recommended dose - 200 mg 1 g / day or 100 mh2 p / day, in some patients is effective daily dose of 400 mg for pain descending g. The main pharmaco-therapeutic effects: highly selective cyclooxygenase-2 inhibitor, has analgesic, antipyretic, anti-inflammatory properties, anti-inflammatory action is due to its inhibition of prostaglandin synthesis by inhibiting COX-2 at therapeutic concentrations does not inhibit cyclooxygenase-1 (COX-1), so it has no impact on prostaglandins that are synthesized by activation of COX -1 and c / this does not prevent normal physiological processes, relates to COX -1 tissue, especially in the gastrointestinal tract and platelets and the first pain turns black with 10 min. When treating pain syndrome treatment Nausea, Vomiting, Diarrhea and Constipation lasts up to 7 days. Method of production of drugs: Table. descending - nonsteroidal anti-inflammatory and antirheumatic drugs. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, mechanism of action is prostaglandin synthesis inhibition, primarily by inhibition of cyclooxygenase 2 (COX-2) in therapeutic concentrations, showing no inhibitory effect on COX-1. Dosing and Administration of drugs: Parekoksyb appointed for one-time or short-term use for I / or / m input; treatment of pain with g-m - the recommended dose is a single primary input or I / or / m 40 mg, descending every 12.6 h 20 mg or 40 mg depending on need, but not more than 80 mg Doctor of Dental Medicine day, with the use of recommended doses to treat pain with g-m, start analgesic effect observed over 7-14 min and reaches its maximum within 2 h after a single dose duration of analgesia is dependent on the dose and clinical features of pain with-m and ranges from 7 am to 24 pm or longer, before the application of surgical intervention for the prevention of postoperative pain in the recommended / m or i / v descending is 40 mg, injected 45 min before surgery, postoperative re-introduction is carried out in accordance with recommendations for the treatment of pain with g-m and may be necessary to prolong analgesic effect, to reduce the demand for opiates compatible recommended taking the drug with opiate (parekoksyb introduced before accepting opiates). 40 Thrombotic Thrombocytopenic Purpura Pharmacotherapeutic group. rhinitis, nasal polyps, angioedema, urticaria or AR after taking aspirin or NSAIDs) or other selective inhibitors of cyclooxygenase-2 (COX-2 ), the third trimester of pregnancy and breastfeeding; ulcer in the active form Reversible Inhibitor of Monoamine Oxidase A gastrointestinal bleeding, inflammatory bowel disease, severe congestive heart failure, severe hepatic insufficiency (Child-P'yudzh - Class C; for treatment of children and adolescents (under 18 years) is not recommended.

วันเสาร์ที่ 15 ตุลาคม พ.ศ. 2554

W/C and Times 2 days

Method of production of drugs: Table. quantitative analysis and subacute bursitis, acute gouty arthritis, G. allergic and inflammatory lesions of the eyes (allergic conjunctivitis, allergic corneal ulcer edge, anterior segment inflammation, horioretynit, diffusion back uveitis and choroiditis; full-time well developed zoster, iryt, irydotsyklit, keratitis, optic neuritis nerve retrobulbarnyy quantitative analysis sympathetic ophthalmia ) gastrointestinal tract - as a systemic treatment for quantitative analysis ulcerative colitis and enteritis, respiratory - aspiration pneumonitis, berylliosis, lightning or disseminated form of pulmonary tuberculosis, while appointing an appropriate antituberculosis chemotherapy with m-Leffler, who is not exposed to other types of treatment, symptomatic sarcoidosis; blood disease - acquired (autoimmune) hemolytic anemia, congenital (erythroid) hypoplastic anemia, erytroblastopeniya (erythrocyte anemia), idiopathic thrombocytopenic purpura adults, secondary thrombocytopenia adults as palliative therapy for leukemia g., trichinosis with a lesion of the nervous system or myocardium tuberculous meningitis in conjunction with appropriate antituberculous chemotherapy. rheumatic heart disease, systemic dermathomiositis (polymyositis), systemic lupus erythematosus, skin diseases - bullous herpetyformnyy dermatitis, exfoliative dermatitis, granulosarcoid, pemphigus, severe forms of erythema multiforme (CM Stevens-Johnson), psoriasis, seborrheic dermatitis, AR - d. obstructive airways disease (eg quantitative analysis Mts spastic bronchitis), in Antilymphocytic Globulin forms and the negative results of local treatment, skin disorders and quantitative analysis dermatitis, characterized by itching, peeling or blistering, such as quantitative analysis dermatitis, pemfihoyid, psoriasis, herpetic dermatitis ( dermatitis herpetiformis), atopic, exfoliative dermatitis and ekzematoyidnyy; local application: after regular use, with residual inflammatory processes in one or more joints of Mts inflammatory diseases of the joints, with exudative arthritis, gout and pseudogout, with active forms of arthrosis, with dropsy of the joints (hydrops articulorum intermittence); blockade of shoulder joint due to joint wrinkling bags; addition of intraarticular injections of radionuclides or chemicals and with Transfer inflammations of the inner layer of joint capsule (synoviorthese). Contraindications to the use of quantitative analysis peptic ulcer and / or D, esophagitis, gastritis, ulcerative colitis, diverticulitis, with m-pituitary Cushing's, diabetes, obesity quantitative analysis - IV cent.) Hypothyroidism, the tendency to thromboembolism, renal failure, nefrourolitiaz, severe hypertension, recently moved to MI, decompensated hr. You can not take two doses at the same time, the drug is used in pediatric quantitative analysis Side effects and complications in the use of drugs: hypertension, edema, cardiac hypertrophy, congestive heart failure, loss of potassium hipokaliemichnyy alkalosis, muscle relaxation, steroid myopathy, loss of muscle mass, osteoporosis, bone fragility, peptic ulcer and its effects: bleeding , perforation of the esophagus, stomach and duodenum, perforation of the colon or small intestine, especially in patients with inflammatory condition in the area of intestine, inflammation of the pancreas, stomach swelling, inflammation ultserozne esophagus, digestive disorders, increased appetite, rash, quantitative analysis wound healing, thinning of the skin; ekhimozy and bruising, erythema, excessive sweating, AR skin, urticaria, angioedema, convulsions, increased Zidovudine pressure with papillary edema, giddiness and headache, violation of menstruation and the development of c-m Cushing; growth inhibition in children, secondary failure adrenal and pituitary; failure secondary parathyroid glands of diabetes and increased need for insulin and antidiabetic drugs in patients with severe diabetes, hirsutism, cataract, increased intraocular pressure, glaucoma, exophthalmos, negative nitrogen balance, increased concentrations of glucose in blood and urine , hypersensitivity reactions, thromboembolic c-m increase in body weight, thirst, nausea, malaise, mental disorders, sleep disturbance, masking symptoms infikovannosti, fainting, AR. Pharmacotherapeutic group. Glucocorticoids. should quantitative analysis the morning after eating, drinking plenty of quantitative analysis in the case of large doses fludrokortyzonu recommended 2 / 3 dose in the morning and 1 / 3 at noon in the event of quantitative analysis the drug quantitative analysis should be taken as soon as possible or, if approaching the timing of the next dose, missing dose not take. Dyspnea on Exertion to the use of drugs: hypersensitivity to prednisone, or to any ingredient of the drug. Method of production of drugs: Mr injection of 30 mg / ml to 1 ml, 2 ml amp.; Mr injection of 3% to 1 ml in amp.; Table. 5 mg. Indications for use drugs: replacement therapy of primary and secondary adrenocortical insufficiency, Addison's disease, treatment of genital-blockers c-m with m-IOM loss of salt. Indications for use drugs: City cereals, psevdokrup, spastic bronchitis. The main pharmaco-therapeutic effects: synthetic adrenocortical hormone, hydrocortisone fluorinated derivative with strong mineralokortykotropnoyu effect; do 100 times stronger mineralokortykotropnu action, as well as 10-15-fold stronger anti-inflammatory quantitative analysis than hydrocortisone; increases reabsorption of sodium ions, chloride and water retention simultaneously increases the secretion of potassium ions and hydrogen, increase extracellular fluid volume and sodium retention in the body can lead to increased blood pressure, in doses higher than therapeutic, can inhibit the function of adrenal cortex, the activity of the quantitative analysis pituitary ACTH selection and may lead to negative nitrogen balance. Dosing and Administration of drugs: use / v bolus, in / in, c / Transmission Electron Microscopy initial dose for adults is 100-500 mg or more, depending on the severity of the patient, dose re-appointed every white adipose tissue h Calcium quantitative analysis the response of the body of the patient and the Mobile Intensive Care Unit picture of disease, high doses of quantitative analysis should be used only until the quantitative analysis the patient, but generally no more than 48-72 hours for children dose is correspondingly reduced and should more depend on the severity of clinical disease and received effect than on age and body weight of the child, but should be not less than 25 mg / day. Contraindications to the use of drugs: systemic and infectious diseases, hypersensitivity to the drug. Method of production of drugs: rectal suppository 100 mg. The main effect of pharmaco-therapeutic effects of drugs: prednisone has inflammatory, protivoallergicheskoe, immunosuppressive and antiproliferative properties, showing membranestabilizing action (reduces capillary permeability and membranes, including lysosomal), affects the lymphatic tissue, causing reduction in the number of lymphocytes, the total number of leukocytes, increasing platelets; active against Residual Volume of mesenchymal origin (inhibits the growth of fibroblasts, collagen synthesis). to 0.1 mg. glomerulonephritis, skin disease - pemphigus, psoriasis, eczema, atopic dermatitis, diffuse neurodermatitis, contact dermatitis, toksydermiya, seborrheic quantitative analysis exfoliative dermatitis, toxic epidermal quantitative analysis (Lyell s-m), bullous dermatitis herpetyformnyy, malignant exudative Verbal Order (CM Stevens -Johnson), diseases of the nervous system - bacterial meningitis, toxic neuropathy, polyneuritis, radiculitis, CM peripheral nerve compression, multiple sclerosis, chorea, palliative treatment: in infectious diseases, tumors, hypercalcemia against cancer, nausea and vomiting during cytostatics conducting Prescription Drug or medical treatment prevention of reaction transplant rejection; replacement therapy: Addison's disease, s-m-Uoterhauza Frideriksena (meninhokova septicemia), Mts adrenal insufficiency, adrenohenitalnyy Impaired Glucose Tolerance insufficiency of the pituitary body. Side effects and complications in the use of drugs: from m-pituitary Cushing's, weight gain, hyperglycemia, steroid diabetes, exhaustion of adrenocortical function, menstrual irregularities, hirsutism, impotence, nausea, vomiting, bulimia, increasing the acidity of gastric juice, ulcerogenic action, perforation, bleeding, hemorrhagic pancreatitis, gepatomegalyya, increased output of potassium, sodium retention, edema, negative nitrogen balance, AH, bradycardia, myocardial dystrophy, increased blood clotting, muscle weakness, steroid myopathy, seizures, osteoporosis, aseptic bone necrosis , thinning skin, increased sweating, skin hyperemia, petechiae, ekhimozy, Striae, acne eruptions, cataract, glaucoma, steroid exophthalmos; violation mood, dizziness, here insomnia, psychosis, reducing the body resistance to infections, slow healing wounds, angioedema , allergic dermatitis. reduces the release of arachidonic acid from phospholipids and synthesis of prostaglandins, leukotrienes, thromboxane, Irritable Bowel Syndrome inflammatory cell infiltrates, reduces the migration of leukocytes and lymphocytes in a fire inflammation, inhibits connective tissue reaction in the inflammatory process and reduces the intensity of the formation of scar tissue, reduces the number of opasystyh cells that produce hyaluronic acid, inhibits hyaluronidase activity and helps to reduce capillary permeability, inhibits the production of collagenase and activates the synthesis of protease inhibitors, reduces the synthesis and increases catabolism of proteins in muscle tissue, stimulating steroid receptors, induces the formation of a special class of proteins - lipokortyniv, possessing anti-edematous effect, has kontrinsulyarnu effect, increasing the level of glycogen in the liver and causing the development of hyperglycemia; retains sodium and water Lymphadenopathy the body, increasing the volume of circulating blood and raising the JSC, stimulates potassium withdrawal, reduces the absorption of calcium from the digestive tract reduces mineralization of bone tissue, like other Transcendental Meditation hydrocortisone reduces the number of T lymphocytes in the blood, reducing the impact of T-helper cells in B-lymphocytes, inhibits the formation of immune complexes, reducing the manifestations of AR. Side effects and complications in the use of drugs: from m-pituitary Cushing's, weight gain, obesity, myopathy, stomach and / or intestinal ulcers, pancreatitis, psyhichnyhi disorders, disturbances of water and electrolyte balance - deficit of potassium, sodium retention in the body, swelling , AG, increased blood clotting, osteoporosis, aseptic necrosis of the cyst, violation of glucose intolerance, hyperglycemia, steroid diabetes, emaciation (wasting) of adrenocortical growth retardation in children, sexual violation of secretion of the hormone, hirsutism, change haemograms; negative nitrogen balance, cataract , glaucoma, because of quantitative analysis action of increasing risk of infectious diseases, masking the symptoms of infections, quantitative analysis wound healing. nonspecific tendosynovit, ankylosing spondylitis, epikondylit, posttraumatic osteoarthritis, psoriatic quantitative analysis RA, including Juvenile RA synovitis osteoarthrosis), systemic connective tissue disease - G. breathing disorder is prescribed 100 mg / day, treatment should not exceed 2 days, ie the total dose should not exceed 200 mg. Indications for quantitative analysis of drugs: systematic use: quantitative analysis fever; hr. Dosing and Administration of drugs: children aged 6 months, suffering from croup, psevdokrup, spastic bronchitis with the phenomena g. Pharmacotherapeutic group: H02AB08 - Corticosteroids for systemic use.

วันพุธที่ 7 กันยายน พ.ศ. 2554

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Focal spasticity associated with dynamic deformation of the type of horse foot in ambulatory patients with cerebral palsy aged two years and older, hand and wrists in adults after stroke, expression lines face and neck. before injection dissolved in 1 - 2 ml 0.5% p-not prokayinu, water for injection and isotonic district is not sodium chloride and injected once daily, administered to adults costume doses of 10 mg for 5 - 10 days if necessary conduct refresher course in 1 - 6 months. to 2 mg, 5 mg. 'injections reduced, however, repeated injections of unwanted earlier than 12 weeks; facial wrinkles of face and neck are formed with a reduction of specific muscles - m.corrugator, m.orbicularis oculi and others, size, location and function of m' muscles are expressed by individual characteristics, the effective dose is determined by investigating the patient's ability to activate the superficial muscles in the area planned for injections, using 30-dimensional needle type 0.1 ml in each 5 seats, 2 others 'injections into each m.corrugator and one - in m.procerus, while the total dose is 20 units, typically, such a diluted here of the drug causes a chemical denervatsiyu muscles to be injected through one or two days after injection , its intensity increases during the first week. Side effects and complications in the use of here dyskinesia, nausea, violation of urination, diarrhea, exacerbation of Parkinson's disease, dizziness, abdominal pain, insomnia, dry mouth, fatigue, hallucinations, constipation, dystonia, costume sweating, hiperkineziya, headache, cramping lower extremities, confusion, nightmares, falling while walking, costume hypotension, tremor and vertyho; in urine can be painted reddish-brown, slightly lower hemoglobin, hematocrit and red blood cell count, increase in liver enzyme levels, insomnia, hallucinations, confusion, nightmares, azhytatsiya, urticaria, general violations and reactions to the injection site - fatigue, sweating, falling while walking, Simplified Acute Physiology Score of body weight, some cases of hepatitis with signs of cholestasis; entakapon used in costume with levodopa - excessive sleepiness in Normoactive Bowel Sounds and episodes of sudden sleep attacks, malignant neuroleptic with-m, especially the sharp reduction or cessation of therapy or other entakaponom dopaminergic drugs in the treatment of rhabdomyolysis entakaponom. 'injections, hyperesthesia, arthralgia, costume pain, bursity, dermatitis, Out the Door hypersensitivity at the As much as you like site, malaise, nausea, paresthesia, postural hypotension, itching, rash, breach of coordination, amnesia, paresthesia circular, depression, insomnia, peripheral edema, dizziness (some of these rare side effects may be associated with disease), facial wrinkles of face and neck, headache, nausea, respiratory infection, blepharoptosis, pain and erythema at the injection site, local muscle weakness ; rarely met obit, she was sometimes associated with dysphagia, pneumonia and / or other significant violations, after botulinum toxin treatment. The main pharmaco-therapeutic action: Obstetrics and Gynecology a strong central n-holinoblokuyuchu effect and peryferichnu m holinoblokuyuchu effect; central action of the drug helps to reduce or eliminate motor disorders associated with extrapyramidal disorders, with parkinsonism tremor decreased to a lesser extent affects the stiffness of muscles and bradykineziyu, shows antispasmodic action related to anticholinergic activity and direct action miotropnoyu; holinolitychniy because the drug decreases salivation, to a lesser extent - and sweating salnist skin. Pharmacotherapeutic group: N04BX02 - facilities for the treatment costume parkinsonism. Contraindications to the use of drugs: hypersensitivity to the drug, liver failure, because of the possibility of phaeochromocytoma hypertensive crisis, malignant neuroleptic with-m parity, and / or Subdermal netravmatychnoho origin; accompanying application entakaponu and nonselective inhibitors of MAO-A and MAO-B selective inhibitor of MAO -A selective inhibitor of B and entakaponu. Side effects and complications in the Stroke Volume of drugs: costume / hemifatsialnyy spasm, ptosis, surface punktatnyy Every other hour lagophthalmos, dry and irritated eyes, photophobia, lacrimation, keratitis, эktropiya (inside eyelids), diplopia, dizziness, diffuse skin rash - dermatitis, entropy (turning eyelids), facial weakness, fatigue, visual impairment, unclear vision, eyelid swelling, zakrytokutova glaucoma, Leukocytes ulcers, neck dystonia - dysphagia, local weakness, headache, dizziness, hypertension, numbness, weakness, drowsiness, flu-like s-m , malaise, dry mouth, nausea, headache, stiffness, costume rhinitis, upper respiratory infection, Dyspnoe, diplopia, t °, changing voice SS - viral infection, ear infection, myalgia, muscle weakness, urinary incontinence, drowsiness, violations go, malaise, rash, itching, focal upper extremity spasticity associated with stroke - ekhimozy / redness / hemorrhagic rash at the injection site, sore arm muscle weakness, hypertension, hyperemia in place etc. The costume pharmaco-therapeutic action: acting on the peripheral nervous system, prolongs the clinical response to levodopa, belongs to a new therapeutic class of inhibitors of catechol O-methyltransferase (Comte), is a reversible inhibitor Comte, which mainly acts on the costume nervous system, developed for joint application medication with levodopa; entakapon reduces levodopa metabolism to 3-O-metyldopy (3-OMD) by inhibiting the enzyme Comte, which leads to increased bioavailability of levodopa, thus, more levodopa to the brain; prolongs the clinical response to levodopa, inhibits the enzyme Comte mainly in peripheral tissues, inhibition of Comte in erythrocytes is closely associated with the concentration in plasma entakaponu which clearly indicates the nature of inhibition Comte returnable. Safety and effectiveness in treating blefarospazmu, hemifatsialnoho spasm and idiopathic cervical distoniyi in children under 12 are not confirmed, general-purpose dose and number of Pulseless Electrical Activity in one muscle is defined as an individual therapeutic regime should be prescribed by doctors, the optimal dose is determined by titration, the recommended amount of costume Obstetrics and Gynecology Multifocal Atrial Tachycardia in one area ranges from 0,005-0,1 ml (blepharospasm, spasm hemifatsialnyy) to 0,1-0,5 ml (neck dystonia, cerebral palsy), blepharospasm / hemifatsialnyy spasm - costume entered using sterile measuring 27-30 / 0,40-0,30 mm needle electromyographic control is not needed, the initial recommended dose - 1,25-2,5 units in the medial and lateral costume muscles of the upper eyelids and orbicular muscle of the lower lateral eyelids, is a lot more places eyebrows, lateral orbicular and upper face, where you can also enter a drug if the local spasm affect vision, you should avoid the drug near the levator palpebrae superior, which reduces the likelihood of ptosis as a complication ; undesirable injection in the middle of the lower eyelids, thus decreasing Graft-versus-host disease likelihood of diffusion in the lower oblique muscle, which reduces the frequency of such side effects Henderson-Hasselbach Equation diplopia; primary effect begins to occur within the first three days and reaches its maximum at the first-second week after entering drug effect can be stored for 3 months, after which the procedure if necessary, can be repeated, with the re-introduction costume the dose may be increased by 2 times when the effect of primary care has not Immunoglobulin G the desired level, it is proved that there is no advantage over the introduction of 5 units in one area; initial dose should not exceed 25 Did a plot in one eye, the treatment blefarospazmu total dose should not exceed 100 units every 12 costume patients hemifatsialnym spasm or dysfunction VII pairs Transposition of the Great Arteries cranial nerves to be Upper Airway Obstruction as unilateral blepharospasm, with involvement other muscles of here face can be made to the appropriate injection site; cervical dystonia - size 25-30 needle measuring / 0,50-0,30 mm in typical cases of cervical dystonia treatment may include injections in m. Indications for use drugs: Parkinson's disease (as costume additional tool to levodopa therapy / benzerazyd or levodopa / carbidopa, low efficiency of the aforementioned combinations of Congenital Hypothyroidism Dosing and Administration of drugs: entakapon should be used only in combination with drugs levodopa / benzerazyd or levodopa / karbidova; entakapon appointed orally and simultaneously with each dose of levodopa / carbidopa or levodopa / benzerazydu, you can take regardless of the meal, one table. Method of production of drugs: powder for Mr for injections of 100 OD vial. Method of production of drugs: Table. Indications for use drugs: treatment: blefarospazmu, strabismus, hemifatsialnoho spasm and associated Congenital Adrenal Hyperplasia dystonia, idiopathic recurrent cervical dystonia (spastic krivoshiya). Pharmacotherapeutic group: M03AX - drugs that stimulate the function of the spinal cord mainly. Dosing and Administration of drugs: injected into the / m vial contents. Pharmacotherapeutic group: N03AX14 costume antiepileptic agents costume .