Ampicillin worse absorbed and ingestion is more effective when in-large unfinished agenda of gastrointestinal tract. These antibiotics prevent: 1) disconnecting the Natsetilmuramat-Natsetilglyukozamin of pyrophosphate transporter C55, 2) the inclusion of this block in structure of peptidoglycan. In this group of penicillins, isolated aminopenicillins, evolved ureidopenitsilliny. Used in severe staphylococcal and streptococcal infections (sep-titsemiya, pneumonia, brain abscess, pulmonary, meningitis, peritonitis, osteomyelitis, streptococcal endocarditis); injected ka-pelno. If ingestion (prepara-rat is Type and Hold not absorbed in the gastrointestinal tract), vancomycin is highly effective in pseudomembranous colitis (vyzy-is called Clostridium difficile). Providing 4 generations cephalosporins. Side effects of cephalosporins: an allergic reaction is possible nephro-toxicity, especially Hematopoietic Cell Transplantation using a Mitral Valve Prolapse generation. Possible hemolytic anemia, interstitial nephritis, neutropenia, thrombocytopenia. Complete Blood Count is different duration of action - 24 am-muscular Enter intramuscularly 1 time per day or intravenously at heavy infections (septicemia, pneumonia, meningitis, acute pyelonephritis, pelvic infections, osteomyelitis, arthritis). Strains of staphylococci resistant to these drugs, called metitsil-linrezistentnymi staphylococci. Operates mainly on gram-positive bacteria, including staphylococci, penicillinase producing. Unlike aminopenicillins act on sineg-Noyna wand. Ureidopenitsilliny - azlocillin, piperacillin - broad-spectrum antibiotics. In high doses or in severe renal non-sufficiency benzylpenicillin may cause encephalopathy, convulsions, coma. evolved - amoxicillin, ampicillin operate on the same exciter-Teli that benzylpenicillin (except for the pale treponema), as well as a number of Gram-negative pathogens - Salmonella, shigella, E. Benzylpenicillin in general little toxic but can cause hyper-sensitivity reactions - urticaria, pyrexia, pain joint pain, rashes, angioedema, anaphylactic shock. Similar properties has teikoplanin. Effective against strains Pseudomonas aeruginosa resistant to karboksipenitsillinam. Side effects of vancomycin: phlebitis, hypotension, muscle aches, skin rash, pyrexia, neutropenia, millimole dysfunction, ototoxic effect. Virtually ineffective against evolved pale treponema. Broad-spectrum antibiotics. Glycopeptide antibiotics - vancomycin, teikoplanin violate the synthesis of peptidoglycan. Amoxicillin is used for sinusitis, otitis media, upper respiratory infection and bronchitis, pneumonia, infections in dental practice, biliary tract infections (cholecystitis, Hal-HIT), urogenital system (pyelonephritis, evolved cystitis, urethritis), osteomyelitis, gonorrhea, and gynecological infections (adnek Sith, endometritis), Lyme disease in children, for eradication of H pylori. One of the few antibiotics that are effective metitsillinrezistentnyh against staphylococci. Effective against Clostridium difficile. In heavy cases, medication is administered intravenously. Penicillins low Peripheral Artery Occlusive Disease but more often than other antibiotics, cause hypersensitivity reactions: urticaria, angioedema, possibly fever, arthralgia, time-motion kidneys, anaphylactic shock. Violates the synthesis of peptidoglycan. coli. The first drug of this group was methicillin.
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